Cellosaurus Vero PVR1/2 DKO hSLAM+ (CVCL_C7UT)
| Cell line name | Vero PVR1/2 DKO hSLAM+ |
|---|---|
| Synonyms | Vero deltaPVR1/2 hSLAM+ c1 |
| Accession | CVCL_C7UT |
| Resource Identification Initiative | To cite this cell line use: Vero PVR1/2 DKO hSLAM+ (RRID:CVCL_C7UT) |
| Comments | Group: Non-human primate cell line. Virology: Not susceptible to infection by poliovirus. Useful for the isolation of measles virus (MeV) and rubella virus (RuV) as both viruses replicate efficiently in this cell line (PubMed=36564197). Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9S1N4; PVR1. Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9S1L1; PVR2. Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:10903; SLAMF1. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P33967; B.cereus Bsr. Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819. Cell type: Epithelial cell of kidney; CL=CL_0002518. |
| Species of origin | Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711) |
| Hierarchy | Parent: CVCL_B3LS (Vero PVR1/2 DKO) |
| Sex of cell | Female |
| Age at sampling | Adult |
| Category | Spontaneously immortalized cell line |
| Publications | PubMed=36564197; DOI=10.1111/1348-0421.13047 |
| Cross-references | |
| Cell line collections (Providers) | JCRB; JCRB1901 |
| Encyclopedic resources | Wikidata; Q123033771 |
| Entry history | |
| Entry creation | 29-Jun-2023 |
| Last entry update | 19-Dec-2024 |
| Version number | 5 |