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Cellosaurus Vero PVR1/2 DKO (CVCL_B3LS)

[Text version]
Cell line name Vero PVR1/2 DKO
Synonyms Vero delta PVR1/2; Vero delta PVR1/2-1
Accession CVCL_B3LS
Resource Identification Initiative To cite this cell line use: Vero PVR1/2 DKO (RRID:CVCL_B3LS)
Comments Group: Non-human primate cell line.
Virology: Not susceptible to infection by poliovirus.
Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9S1N4; PVR1.
Knockout cell: Method=CRISPR/Cas9; UniProtKB; A0A0D9S1L1; PVR2.
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Simia sabaea) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_B3LR (Vero PVR1 KO)
Children:
CVCL_C7UT (Vero PVR1/2 DKO hSLAM+)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=33762624; DOI=10.1038/s41598-021-86050-3; PMCID=PMC7991635
Okemoto-Nakamura Y., Someya K., Yamaji T., Saito K., Takeda M., Hanada K.
Poliovirus-nonsusceptible Vero cell line for the World Health Organization global action plan.
Sci. Rep. 11:6746-6746(2021)

Cross-references
Cell line collections (Providers) JCRB; JCRB1840
Encyclopedic resources Wikidata; Q110433961
Entry history
Entry creation16-Dec-2021
Last entry update05-Oct-2023
Version number6