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Cellosaurus Sui75 (CVCL_C7UK)

[Text version]
Cell line name Sui75
Accession CVCL_C7UK
Resource Identification Initiative To cite this cell line use: Sui75 (RRID:CVCL_C7UK)
Comments Population: Japanese.
Characteristics: Established from the 75Taco21 SCID nude mouse xenograft.
Doubling time: 30.3 hours (PubMed=35272288).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=35272288).
  • Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=35272288).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (PubMed=35272288).
  • Mutation; HGNC; HGNC:11100; SMARCA4; Simple; p.Gly1611fs*15 (c.4830_4833delGGGC); Zygosity=Heterozygous (PubMed=35272288).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr231fs*8 (c.691_692delAC); Zygosity=Homozygous (PubMed=35272288).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C7UL ! Sui76
Sex of cell Male
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1925

Markers:
AmelogeninX,Y
CSF1PO11,12
D5S8188,11
D7S82011
D13S3179,12
D16S5399
TH016
TPOX9
vWA17,19

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Publications

PubMed=35272288; DOI=10.1159/000521714
Yanagihara K., Iino Y., Yokozaki H., Kubo T., Oda T., Kubo T., Komatsu M., Sasaki H., Ichikawa H., Kuwata T., Seyama T., Ochiai A.
A comparative study of patient-derived tumor models of pancreatic ductal adenocarcinoma involving orthotopic implantation.
Pathobiology 89:222-232(2022)

Cross-references
Cell line collections (Providers) JCRB; JCRB1925
Encyclopedic resources Wikidata; Q123033568
Gene expression databases GEO; GSM4767173
Entry history
Entry creation29-Jun-2023
Last entry update19-Dec-2024
Version number4