ID   Sui75
AC   CVCL_C7UK
DR   GEO; GSM4767173
DR   JCRB; JCRB1925
DR   Wikidata; Q123033568
RX   PubMed=35272288;
CC   Population: Japanese.
CC   Characteristics: Established from the 75Taco21 SCID nude mouse xenograft.
CC   Doubling time: 30.3 hours (PubMed=35272288).
CC   Sequence variation: Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=35272288).
CC   Sequence variation: Gene deletion; HGNC; HGNC:6770; SMAD4; Zygosity=Homozygous (PubMed=35272288).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (PubMed=35272288).
CC   Sequence variation: Mutation; HGNC; HGNC:11100; SMARCA4; Simple; p.Gly1611fs*15 (c.4830_4833delGGGC); Zygosity=Heterozygous (PubMed=35272288).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr231fs*8 (c.691_692delAC); Zygosity=Homozygous (PubMed=35272288).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
ST   Source(s): JCRB=JCRB1925
ST   Amelogenin: X,Y
ST   CSF1PO: 11,12
ST   D13S317: 9,12
ST   D16S539: 9
ST   D5S818: 8,11
ST   D7S820: 11
ST   TH01: 6
ST   TPOX: 9
ST   vWA: 17,19
DI   NCIt; C8294; Pancreatic adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C7UL ! Sui76
SX   Male
AG   76Y
CA   Cancer cell line
DT   Created: 29-06-23; Last updated: 19-12-24; Version: 4
//
RX   PubMed=35272288; DOI=10.1159/000521714;
RA   Yanagihara K., Iino Y., Yokozaki H., Kubo T., Oda T., Kubo T.,
RA   Komatsu M., Sasaki H., Ichikawa H., Kuwata T., Seyama T., Ochiai A.;
RT   "A comparative study of patient-derived tumor models of pancreatic
RT   ductal adenocarcinoma involving orthotopic implantation.";
RL   Pathobiology 89:222-232(2022).
//