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Cellosaurus HMS50 (CVCL_C7T2)

[Text version]
Cell line name HMS50
Accession CVCL_C7T2
Resource Identification Initiative To cite this cell line use: HMS50 (RRID:CVCL_C7T2)
Comments Senescence: Capable of 40-50 PDL. One clone senesced at 68 PDL (PubMed=7799951).
Derived from site: In situ; Breast, interlobular stroma; UBERON=UBERON_8480033.
Cell type: Fibroblast; CL=CL_0000057.
Sequence variations
Disease Li-Fraumeni syndrome (NCIt: C3476)
Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C7SZ (HMS50-E6/E7-2)CVCL_C7T0 (HMS50-E7-5)
Originate from same individual CVCL_C7T1 ! HME50
Sex of cell Female
Age at sampling 31Y
Category Finite cell line
Publications

PubMed=7799951; DOI=10.1128/mcb.15.1.425; PMCID=PMC231985
Shay J.W., Tomlinson G.E., Piatyszek M.A., Gollahon L.S.
Spontaneous in vitro immortalization of breast epithelial cells from a patient with Li-Fraumeni syndrome.
Mol. Cell. Biol. 15:425-432(1995)

Cross-references
Encyclopedic resources Wikidata; Q117704494
Entry history
Entry creation21-Mar-2023
Last entry update19-Dec-2024
Version number3