Cellosaurus STF3a (CVCL_C6NQ)
| Cell line name | STF3a |
|---|---|
| Accession | CVCL_C6NQ |
| Resource Identification Initiative | To cite this cell line use: STF3a (RRID:CVCL_C6NQ) |
| Comments | Characteristics: Stably express high levels of murine Wnt3a (PubMed=19022675). Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (from parent cell line). Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:98956; Wnt3a. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_AQ26 (HEK 293 STF) |
| Sex of cell | Female |
| Age at sampling | Fetus |
| Category | Transformed cell line |
| Publications | PubMed=19022675; DOI=10.1016/j.bmc.2008.10.077; PMCID=PMC2670876 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q117704897 |
| Entry history | |
| Entry creation | 21-Mar-2023 |
| Last entry update | 10-Sep-2024 |
| Version number | 3 |