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Cellosaurus STF3a (CVCL_C6NQ)

[Text version]
Cell line name STF3a
Accession CVCL_C6NQ
Resource Identification Initiative To cite this cell line use: STF3a (RRID:CVCL_C6NQ)
Comments Characteristics: Stably express high levels of murine Wnt3a (PubMed=19022675).
Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (from parent cell line).
Transfected with: MGI; MGI:98956; Wnt3a.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_AQ26 (HEK 293 STF)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=19022675; DOI=10.1016/j.bmc.2008.10.077
McCulloch M.W.B., Coombs G.S., Banerjee N., Bugni T.S., Cannon K.M., Harper M.K., Veltri C.A., Virshup D.M., Ireland C.M.
Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives.
Bioorg. Med. Chem. 17:2189-2198(2009)

Cross-references
Encyclopedic resources Wikidata; Q117704897
Entry history
Entry creation21-Mar-2023
Last entry update29-Jun-2023
Version number2