Cellosaurus HEK 293 STF (CVCL_AQ26)
| Cell line name | HEK 293 STF | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Synonyms | STF; Super TOP-FLASH; SuperTopFlash | ||||||||||||||||||
| Accession | CVCL_AQ26 | ||||||||||||||||||
| Resource Identification Initiative | To cite this cell line use: HEK 293 STF (RRID:CVCL_AQ26) | ||||||||||||||||||
| Comments | Characteristics: Responds to activation of the canonical Wnt signaling pathway by increasing expression of firefly luciferase. Luciferase reporter gene expression is under the control of a promoter with 7 LEF/TCF binding sites (PubMed=15035989). Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Firefly luciferase. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Adenovirus 5. Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113. | ||||||||||||||||||
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||
| Hierarchy | Parent: CVCL_0045 (HEK293) Children:
| ||||||||||||||||||
| Sex of cell | Female | ||||||||||||||||||
| Age at sampling | Fetus | ||||||||||||||||||
| Category | Transformed cell line | ||||||||||||||||||
| STR profile | Source(s): ATCC=CRL-3249 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||
| Publications | PubMed=15035989; DOI=10.1016/S0092-8674(04)00216-8 | ||||||||||||||||||
| Cross-references | |||||||||||||||||||
| Cell line collections (Providers) | ATCC; CRL-3249
Kerafast; EJH014 | ||||||||||||||||||
| Encyclopedic resources | Wikidata; Q54882278 | ||||||||||||||||||
| Entry history | |||||||||||||||||||
| Entry creation | 02-May-2016 | ||||||||||||||||||
| Last entry update | 10-Sep-2024 | ||||||||||||||||||
| Version number | 13 | ||||||||||||||||||