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Cellosaurus GI-CO-T-9 (CVCL_C5WN)

[Text version]
Cell line name GI-CO-T-9
Synonyms Gaslini Institute-CO-T cell-9
Accession CVCL_C5WN
Resource Identification Initiative To cite this cell line use: GI-CO-T-9 (RRID:CVCL_C5WN)
Comments Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1574Pro (c.4721T>C); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7881; NOTCH1; Simple; p.Pro2493fs*67 (c.7476_7477ins11); Zygosity=Heterozygous (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1641 (PF-382)
Sex of cell Female
Age at sampling 6Y
Category Cancer cell line
Publications

PubMed=3210814
Montaldo P.G., Lanciotti M., Castagnola E., Parodi M.T., Cirillo C., Cornaglia-Ferraris P., Ponzoni M.
A human acute leukemia-derived T-cell line produces two inhibitor factors which suppress lymphocyte proliferation: characterization and purification of the molecules.
Lymphokine Res. 7:413-427(1988)

PubMed=3257694; DOI=10.1016/0006-291x(88)90448-2
Ponzoni M., Montaldo P.G., Lanciotti M., Castagnola E., Cirillo C., Cornaglia-Ferraris P.
Purification to homogeneity and biochemical characterization of two suppressor factors from human malignant T-cells.
Biochem. Biophys. Res. Commun. 150:702-710(1988)

Cross-references
Encyclopedic resources Wikidata; Q116049077
Entry history
Entry creation15-Dec-2022
Last entry update29-Jun-2023
Version number3