ID   GI-CO-T-9
AC   CVCL_C5WN
SY   Gaslini Institute-CO-T cell-9
DR   Wikidata; Q116049077
RX   PubMed=3210814;
RX   PubMed=3257694;
CC   Population: Caucasian.
CC   Sequence variation: Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1574Pro (c.4721T>C); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7881; NOTCH1; Simple; p.Pro2493fs*67 (c.7476_7477ins11); Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C7953; Childhood T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1641 ! PF-382
SX   Female
AG   6Y
CA   Cancer cell line
DT   Created: 15-12-22; Last updated: 29-06-23; Version: 3
//
RX   PubMed=3210814;
RA   Montaldo P.G., Lanciotti M., Castagnola E., Parodi M.T., Cirillo C.,
RA   Cornaglia-Ferraris P., Ponzoni M.;
RT   "A human acute leukemia-derived T-cell line produces two inhibitor
RT   factors which suppress lymphocyte proliferation: characterization and
RT   purification of the molecules.";
RL   Lymphokine Res. 7:413-427(1988).
//
RX   PubMed=3257694; DOI=10.1016/0006-291x(88)90448-2;
RA   Ponzoni M., Montaldo P.G., Lanciotti M., Castagnola E., Cirillo C.,
RA   Cornaglia-Ferraris P.;
RT   "Purification to homogeneity and biochemical characterization of two
RT   suppressor factors from human malignant T-cells.";
RL   Biochem. Biophys. Res. Commun. 150:702-710(1988).
//