| Cell line name |
LG2 |
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| Synonyms |
LG-2 |
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| Accession |
CVCL_C5UW |
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| Resource Identification Initiative |
To cite this cell line use: LG2 (RRID:CVCL_C5UW) |
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| Comments |
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: HLA class II peptidome analysis by proteomics.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178. |
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| HLA typing |
Source: PubMed=25469497
| Class I | | HLA-A | A*02 | | HLA-B | B*27:05 | | HLA-C | C*01 |
Source: PubMed=12133989
| Class I | | HLA-A | A*02 | | HLA-B | B*27:05:02 | | HLA-C | C*01 | | Class II | | HLA-DP | DPA1*01:01 | | DPB1*02:01 | | HLA-DQ | DQA1*01:01 | | DQB1*05:01 | | HLA-DR | DRB1*01:01 |
Source: IPD-IMGT/HLA=10984
| Class I | | HLA-B | B*02:01,27:05 | | Class II | | HLA-DP | DPA1*01:03:01:01 | | HLA-DQ | DQA1*01:01:01:01 | | DQB1*05:01:01:01 | | HLA-DR | DRB1*01:01:01:01 |
|
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Children:
|
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| Sex of cell |
Male |
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| Category |
Transformed cell line |
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| Publications | PubMed=2824477; DOI=10.1016/S0021-9258(18)47699-5
Gorga J.C., Horejsi V., Johnson D.R., Raghupathy R., Strominger J.L.
Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line.
J. Biol. Chem. 262:16087-16094(1987) PubMed=12133989; DOI=10.4049/jimmunol.169.3.1593
Paludan C., Bickham K., Nikiforow S., Tsang M.L., Goodman K., Hanekom W.A., Fonteneau J.-F., Stevanovic S., Munz C.
Epstein-Barr nuclear antigen 1-specific CD4(+) Th1 cells kill Burkitt's lymphoma cells.
J. Immunol. 169:1593-1603(2002) PubMed=25469497; DOI=10.1002/art.38980
Sanz-Bravo A., Campos J., Mazariegos M.S., Lopez de Castro J.A.
Dominant role of the ERAP1 polymorphism R528K in shaping the HLA-B27 peptidome through differential processing determined by multiple peptide residues.
Arthritis Rheumatol. 67:692-701(2015) PubMed=30573663; DOI=10.1074/mcp.RA118.000956; PMCID=PMC6398211
Nanaware P.P., Jurewicz M.M., Leszyk J.D., Shaffer S.A., Stern L.J.
HLA-DO modulates the diversity of the MHC-II self-peptidome.
Mol. Cell. Proteomics 18:490-503(2019) |
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| Cross-references |
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| Cell line databases/resources |
IPD-IMGT/HLA; 10984
|
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| Encyclopedic resources |
Wikidata; Q116049680
|
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| Proteomic databases |
PRIDE; PXD008500
PRIDE; PXD010301
|
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| Entry history |
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| Entry creation | 15-Dec-2022 |
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| Last entry update | 29-Jun-2023 |
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| Version number | 3 |
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