ID   LG2
AC   CVCL_C5UW
SY   LG-2
DR   IPD-IMGT/HLA; 10984
DR   PRIDE; PXD008500
DR   PRIDE; PXD010301
DR   Wikidata; Q116049680
RX   PubMed=2824477;
RX   PubMed=12133989;
RX   PubMed=25469497;
RX   PubMed=30573663;
CC   HLA typing: A*02; B*27:05; C*01 (PubMed=25469497).
CC   HLA typing: A*02; B*27:05:02; C*01; DPA1*01:01; DPB1*02:01; DQA1*01:01; DQB1*05:01; DRB1*01:01 (PubMed=12133989).
CC   HLA typing: B*02:01,27:05; DPA1*01:03:01:01; DQA1*01:01:01:01; DQB1*05:01:01:01; DRB1*01:01:01:01 (IPD-IMGT/HLA=10984).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: HLA class II peptidome analysis by proteomics.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Transformed cell line
DT   Created: 15-12-22; Last updated: 29-06-23; Version: 3
//
RX   PubMed=2824477; DOI=10.1016/S0021-9258(18)47699-5;
RA   Gorga J.C., Horejsi V., Johnson D.R., Raghupathy R., Strominger J.L.;
RT   "Purification and characterization of class II histocompatibility
RT   antigens from a homozygous human B cell line.";
RL   J. Biol. Chem. 262:16087-16094(1987).
//
RX   PubMed=12133989; DOI=10.4049/jimmunol.169.3.1593;
RA   Paludan C., Bickham K., Nikiforow S., Tsang M.L., Goodman K.,
RA   Hanekom W.A., Fonteneau J.-F., Stevanovic S., Munz C.;
RT   "Epstein-Barr nuclear antigen 1-specific CD4(+) Th1 cells kill
RT   Burkitt's lymphoma cells.";
RL   J. Immunol. 169:1593-1603(2002).
//
RX   PubMed=25469497; DOI=10.1002/art.38980;
RA   Sanz-Bravo A., Campos J., Mazariegos M.S., Lopez de Castro J.A.;
RT   "Dominant role of the ERAP1 polymorphism R528K in shaping the HLA-B27
RT   peptidome through differential processing determined by multiple
RT   peptide residues.";
RL   Arthritis Rheumatol. 67:692-701(2015).
//
RX   PubMed=30573663; DOI=10.1074/mcp.RA118.000956; PMCID=PMC6398211;
RA   Nanaware P.P., Jurewicz M.M., Leszyk J.D., Shaffer S.A., Stern L.J.;
RT   "HLA-DO modulates the diversity of the MHC-II self-peptidome.";
RL   Mol. Cell. Proteomics 18:490-503(2019).
//