Cellosaurus H9 AAVS1-TRE3G-NGN2 PINK1-/- (CVCL_C4EM)
| Cell line name | H9 AAVS1-TRE3G-NGN2 PINK1-/- |
|---|---|
| Accession | CVCL_C4EM |
| Resource Identification Initiative | To cite this cell line use: H9 AAVS1-TRE3G-NGN2 PINK1-/- (RRID:CVCL_C4EM) |
| Comments | Characteristics: Using CRISPR/Cas9 a TRE3G promoter driven NEUROG2 construct was introduced in the AAVS1 safe harbor locus (from parent cell line). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:14581; PINK1. Genetic integration: Method=CRISPR/Cas9; Gene=HGNC; HGNC:13805; NEUROG2. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C4EK (H9 AAVS1-TRE3G-NGN2) |
| Sex of cell | Female |
| Age at sampling | Blastocyst stage |
| Category | Embryonic stem cell |
| Publications | PubMed=34699746; DOI=10.1016/j.molcel.2021.10.001; PMCID=PMC8688335 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q116049277 |
| Entry history | |
| Entry creation | 15-Dec-2022 |
| Last entry update | 19-Dec-2024 |
| Version number | 5 |