ID   H9 AAVS1-TRE3G-NGN2 PINK1-/-
AC   CVCL_C4EM
DR   Wikidata; Q116049277
RX   PubMed=34699746;
CC   Characteristics: Using CRISPR/Cas9 a TRE3G promoter driven NEUROG2 construct was introduced in the AAVS1 safe harbor locus (from parent cell line).
CC   Knockout cell: Method=CRISPR/Cas9; HGNC; 14581; PINK1.
CC   Transfected with: HGNC; 13805; NEUROG2.
CC   Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
CC   Cell type: Embryonic stem cell; CL=CL_0002322.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C4EK ! H9 AAVS1-TRE3G-NGN2
SX   Female
AG   Blastocyst stage
CA   Embryonic stem cell
DT   Created: 15-12-22; Last updated: 29-06-23; Version: 3
//
RX   PubMed=34699746; DOI=10.1016/j.molcel.2021.10.001;
RA   Ordureau A., Kraus F., Zhang J.-C., An H., Park S., Ahfeldt T.,
RA   Paulo J.A., Harper J.W.;
RT   "Temporal proteomics during neurogenesis reveals large-scale proteome
RT   and organelle remodeling via selective autophagy.";
RL   Mol. Cell 81:5082-5098.e11(2021).
//