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Cellosaurus CuFi-3 (CVCL_C458)

[Text version]
Cell line name CuFi-3
Synonyms CuFi3; Cystic Fibrosis, University of Iowa-3
Accession CVCL_C458
Resource Identification Initiative To cite this cell line use: CuFi-3 (RRID:CVCL_C458)
Comments Karyotypic information: 48,XY,+5,+20 [10] (PubMed=12676769).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Sequence variations
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 15Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-4014

Markers:
AmelogeninX,Y
CSF1PO10,13
D5S81811,12
D7S82010,11
D13S31711,12
D16S53912,13
TH019,9.3
TPOX10,11
vWA16,19

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Publications

PubMed=12676769; DOI=10.1152/ajplung.00355.2002
Zabner J., Karp P., Seiler M., Phillips S.L., Mitchell C.J., Saavedra M.T., Welsh M., Klingelhutz A.J.
Development of cystic fibrosis and noncystic fibrosis airway cell lines.
Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L844-L854(2003)

PubMed=17191107; DOI=10.1007/s10238-006-0116-5
Gambardella S., Biancolella M., D'Apice M.R., Amati F., Sangiuolo F., Farcomeni A., Chillemi G., Bueno S., Desideri A., Novelli G.
Gene expression profile study in CFTR mutated bronchial cell lines.
Clin. Exp. Med. 6:157-165(2006)

Cross-references
Cell line collections (Providers) ATCC; CRL-4014 - Discontinued
CancerTools; 154446
Biological sample resources BioSample; SAMN03471723
Encyclopedic resources Wikidata; Q54814856
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number26