ID   CuFi-3
AC   CVCL_C458
SY   CuFi3; Cystic Fibrosis, University of Iowa-3
DR   ATCC; CRL-4014
DR   BioSample; SAMN03471723
DR   CancerTools; 154446
DR   Wikidata; Q54814856
RX   PubMed=12676769;
RX   PubMed=17191107;
CC   Karyotypic information: 48,XY,+5,+20 [10] (PubMed=12676769).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Phe508del (c.1521_1523delCTT); ClinVar=VCV000007105; Zygosity=Heterozygous (PubMed=12676769).
CC   Sequence variation: Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Arg553Ter (c.1657C>T); ClinVar=VCV000007122; Zygosity=Heterozygous (PubMed=12676769).
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Omics: Transcriptome analysis by microarray.
CC   Discontinued: ATCC; CRL-4014; true.
CC   Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
CC   Cell type: Epithelial cell of bronchus; CL=CL_0002328.
ST   Source(s): ATCC=CRL-4014
ST   Amelogenin: X,Y
ST   CSF1PO: 10,13
ST   D13S317: 11,12
ST   D16S539: 12,13
ST   D5S818: 11,12
ST   D7S820: 10,11
ST   TH01: 9,9.3
ST   TPOX: 10,11
ST   vWA: 16,19
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   15Y
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 26
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RX   PubMed=12676769; DOI=10.1152/ajplung.00355.2002;
RA   Zabner J., Karp P., Seiler M., Phillips S.L., Mitchell C.J.,
RA   Saavedra M.T., Welsh M., Klingelhutz A.J.;
RT   "Development of cystic fibrosis and noncystic fibrosis airway cell
RT   lines.";
RL   Am. J. Physiol. Lung Cell. Mol. Physiol. 284:L844-L854(2003).
//
RX   PubMed=17191107; DOI=10.1007/s10238-006-0116-5;
RA   Gambardella S., Biancolella M., D'Apice M.R., Amati F., Sangiuolo F.,
RA   Farcomeni A., Chillemi G., Bueno S., Desideri A., Novelli G.;
RT   "Gene expression profile study in CFTR mutated bronchial cell lines.";
RL   Clin. Exp. Med. 6:157-165(2006).
//