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Cellosaurus SVG-A CHMP1A null (CVCL_C3HJ)

[Text version]
Cell line name SVG-A CHMP1A null
Accession CVCL_C3HJ
Resource Identification Initiative To cite this cell line use: SVG-A CHMP1A null (RRID:CVCL_C3HJ)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8740; CHMP1A.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5G13 (SVG-A)
Sex of cell Male
Age at sampling 8-12FW
Category Transformed cell line
Publications

PubMed=30044992; DOI=10.1016/j.celrep.2018.06.100; PMCID=PMC6178983
Coulter M.E., Dorobantu C.M., Lodewijk G.A., Delalande F., Cianferani S., Ganesh V.S., Smith R.S., Lim E.T.-T., Xu C.S., Pang S., Wong E.T., Lidov H.G.W., Calicchio M.L., Yang E., Gonzalez D.M., Schlaeger T.M., Mochida G.H., Hess H., Lee W.-C.A., Lehtinen M.K., Kirchhausen T.L., Haussler D., Jacobs F.M.J., Gaudin R., Walsh C.A.
The ESCRT-III protein CHMP1A mediates secretion of sonic hedgehog on a distinctive subtype of extracellular vesicles.
Cell Rep. 24:973-986.e8(2018)

Cross-references
Encyclopedic resources Wikidata; Q114313073
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7