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Cellosaurus SVG-A CHMP1A null (CVCL_C3HJ)

[Text version]
Cell line name SVG-A CHMP1A null
Accession CVCL_C3HJ
Resource Identification Initiative To cite this cell line use: SVG-A CHMP1A null (RRID:CVCL_C3HJ)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:8740; CHMP1A.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5G13 (SVG-A)
Sex of cell Male
Age at sampling 8-12FW
Category Transformed cell line
Publications

PubMed=30044992; DOI=10.1016/j.celrep.2018.06.100; PMCID=PMC6178983
Coulter M.E., Dorobantu C.M., Lodewijk G.A., Delalande F., Cianferani S., Ganesh V.S., Smith R.S., Lim E.T., Xu C.S., Pang S., Wong E.T., Lidov H.G.W., Calicchio M.L., Yang E., Gonzalez D.M., Schlaeger T.M., Mochida G.H., Hess H., Lee W.-C.A., Lehtinen M.K., Kirchhausen T.L., Haussler D., Jacobs F.M.J., Gaudin R., Walsh C.A.
The ESCRT-III protein CHMP1A mediates secretion of sonic hedgehog on a distinctive subtype of extracellular vesicles.
Cell Rep. 24:973-986.e8(2018)

Cross-references
Encyclopedic resources Wikidata; Q114313073
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7