Cellosaurus A549 EGFR Biosensor (CVCL_C3ET)
| Cell line name | A549 EGFR Biosensor |
|---|---|
| Synonyms | A549 EGFR SH2 Biosensor |
| Accession | CVCL_C3ET |
| Resource Identification Initiative | To cite this cell line use: A549 EGFR Biosensor (RRID:CVCL_C3ET) |
| Comments | Population: Caucasian. Characteristics: Within minutes after stimulation of the cell line with EGF, the biosensor shows robust redistribution towards the cell membrane and subsequent internalization through endocytosis (Sigma-Aldrich). Characteristics: Transduced with a TagGFP2-SH2-SH2 construct. Transfected with: UniProtKB; Q8WTC6; Aequorea macrodactyla GFP (with p.Lys3Gly, p.Thr9Ala, p.Ser65Cys, p.Phe99Gln, p.Met128Lys, p.Asn144Ser, p.Met153Arg, p.Lys162Glu, p.Val163Ala, p.Ile167Thr, p.Ala206Lys, p.Thr214Ala, p.Phe220Leu, p.Phe223Ser, p.Gly228Cys and Lys238Arg = TagGFP2). Derived from site: In situ; Lung; UBERON=UBERON_0002048. |
| Sequence variations |
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| Disease | Lung adenocarcinoma (NCIt: C3512) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0023 (A-549) |
| Sex of cell | Male |
| Age at sampling | 58Y |
| Category | Cancer cell line |
| Web pages | https://www.sigmaaldrich.com/catalog/product/sigma/cll1097 |
| Cross-references | |
| Cell line databases/resources | cancercelllines; CVCL_C3ET |
| Encyclopedic resources | Wikidata; Q114310513 |
| Entry history | |
| Entry creation | 22-Sep-2022 |
| Last entry update | 05-Oct-2023 |
| Version number | 5 |