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Cellosaurus OMM2.3 (CVCL_C306)

[Text version]
Cell line name OMM2.3
Synonyms Omm2.3; OMM2_3; OMM-2.3; OMM 2-3; OMM1.3; Omm1_3; OMM1_3
Accession CVCL_C306
Resource Identification Initiative To cite this cell line use: OMM2.3 (RRID:CVCL_C306)
Comments From: Ksander, Bruce R.; Schepens Eye Research Institute; Boston; USA.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C302 ! Mel270
CVCL_C305 ! OMM2.2
CVCL_C307 ! OMM2.5
CVCL_C308 ! OMM2.6
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=22236444

Markers:
AmelogeninX,Y
CSF1PO11
D3S135816
D5S81812
D7S8208,9
D13S31712
D16S53912
FGA26
TH016,9
TPOX10
vWA17,18

Run an STR similarity search on this cell line
Publications

PubMed=9247253; DOI=10.1023/A:1018479011340
Chen P.W., Murray T.G., Uno T., Salgaller M.L., Reddy R., Ksander B.R.
Expression of MAGE genes in ocular melanoma during progression from primary to metastatic disease.
Clin. Exp. Metastasis 15:509-518(1997)

PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016
White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.
Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.
Cancer Genet. Cytogenet. 168:11-21(2006)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

PubMed=28018010; PMCID=PMC5161001
Jager M.J., Bermudez Magner J.A., Ksander B.R., Dubovy S.R.
Uveal melanoma cell lines: where do they come from? (an American Ophthalmological Society thesis).
Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016)

PubMed=32430489; DOI=10.1158/1535-7163.MCT-19-1016; PMCID=PMC7415561
Teh J.L.F., Purwin T.J., Han A., Chua V., Patel P., Baqai U., Liao C., Bechtel N., Sato T., Davies M.A., Aguirre-Ghiso J.A., Aplin A.E.
Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal melanoma.
Mol. Cancer Ther. 19:1719-1726(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C306
Cell_Model_Passport; SIDM01844
Encyclopedic resources Wikidata; Q54936372
Polymorphism and mutation databases Cosmic; 899900
Cosmic; 916145
Cosmic; 1628397
Cosmic; 1669127
Cosmic; 2036705
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number20