ID   OMM2.3
AC   CVCL_C306
SY   Omm2.3; OMM2_3; OMM-2.3; OMM 2-3; OMM1.3; Omm1_3; OMM1_3
DR   cancercelllines; CVCL_C306
DR   Cell_Model_Passport; SIDM01844
DR   Cosmic; 899900
DR   Cosmic; 916145
DR   Cosmic; 1628397
DR   Cosmic; 1669127
DR   Cosmic; 2036705
DR   Wikidata; Q54936372
RX   PubMed=9247253;
RX   PubMed=16772116;
RX   PubMed=22236444;
RX   PubMed=28018010;
RX   PubMed=32430489;
CC   From: Ksander, Bruce R.; Schepens Eye Research Institute; Boston; USA.
CC   Sequence variation: Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.Gln209Pro (c.626A>C); ClinVar=VCV000375957; Zygosity=Unspecified (PubMed=22236444).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
ST   Source(s): PubMed=22236444
ST   Amelogenin: X,Y
ST   CSF1PO: 11
ST   D13S317: 12
ST   D16S539: 12
ST   D3S1358: 16
ST   D5S818: 12
ST   D7S820: 8,9
ST   FGA: 26
ST   TH01: 6,9
ST   TPOX: 10
ST   vWA: 17,18
DI   NCIt; C7712; Uveal melanoma
DI   ORDO; Orphanet_39044; Uveal melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C302 ! Mel270
OI   CVCL_C305 ! OMM2.2
OI   CVCL_C307 ! OMM2.5
OI   CVCL_C308 ! OMM2.6
SX   Male
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 20
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RX   PubMed=9247253; DOI=10.1023/A:1018479011340;
RA   Chen P.W., Murray T.G., Uno T., Salgaller M.L., Reddy R.,
RA   Ksander B.R.;
RT   "Expression of MAGE genes in ocular melanoma during progression from
RT   primary to metastatic disease.";
RL   Clin. Exp. Metastasis 15:509-518(1997).
//
RX   PubMed=16772116; DOI=10.1016/j.cancergencyto.2005.11.016;
RA   White J.S., Becker R.L., McLean I.W., Director-Myska A.E., Nath J.;
RT   "Molecular cytogenetic evaluation of 10 uveal melanoma cell lines.";
RL   Cancer Genet. Cytogenet. 168:11-21(2006).
//
RX   PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394;
RA   Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K.,
RA   Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.;
RT   "Genetic and molecular characterization of uveal melanoma cell
RT   lines.";
RL   Pigment Cell Melanoma Res. 25:182-187(2012).
//
RX   PubMed=28018010; PMCID=PMC5161001;
RA   Jager M.J., Bermudez Magner J.A., Ksander B.R., Dubovy S.R.;
RT   "Uveal melanoma cell lines: where do they come from? (an American
RT   Ophthalmological Society thesis).";
RL   Trans. Am. Ophthalmol. Soc. 114:T5-T5(2016).
//
RX   PubMed=32430489; DOI=10.1158/1535-7163.MCT-19-1016; PMCID=PMC7415561;
RA   Teh J.L.F., Purwin T.J., Han A., Chua V., Patel P., Baqai U., Liao C.,
RA   Bechtel N., Sato T., Davies M.A., Aguirre-Ghiso J.A., Aplin A.E.;
RT   "Metabolic adaptations to MEK and CDK4/6 cotargeting in uveal
RT   melanoma.";
RL   Mol. Cancer Ther. 19:1719-1726(2020).
//