Cellosaurus logo
expasy logo

Cellosaurus WM858 (CVCL_C283)

[Text version]
Cell line name WM858
Synonyms WM-858; WM 858; Wm858; WML-858
Accession CVCL_C283
Resource Identification Initiative To cite this cell line use: WM858 (RRID:CVCL_C283)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L030 ! WM740V
CVCL_C284 ! WM873-1
CVCL_C285 ! WM873-2
CVCL_C286 ! WM873-3
Sex of cell Female
Age at sampling 48Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO11,12
D2S133822,23
D3S135817
D5S81810,12
D7S8209,10
D8S117912,13
D13S31711
D16S5398,12
D18S5114
D19S43313,15
D21S1129,32.2
FGA20,23
TH016,8
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=3856042; DOI=10.1093/jnci/74.2.283
Herlyn M., Balaban-Malenbaum G.B., Bennicelli J.L., Guerry D. 4th, Halaban R., Herlyn D., Elder D.E., Maul G.G., Steplewski Z., Nowell P.C., Clark W.H. Jr., Koprowski H.
Primary melanoma cells of the vertical growth phase: similarities to metastatic cells.
J. Natl. Cancer Inst. 74:283-289(1985)

PubMed=4053039
Herlyn M., Thurin J., Balaban-Malenbaum G.B., Bennicelli J.L., Herlyn D., Elder D.E., Bondi E., Guerry D. 4th, Nowell P.C., Clark W.H. Jr., Koprowski H.
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18632627; DOI=10.1158/0008-5472.CAN-08-0235; PMCID=PMC2615688
Smalley K.S.M., Contractor R., Nguyen T.K., Xiao M., Edwards R., Muthusamy V., King A.J., Flaherty K.T., Bosenberg M.W., Herlyn M., Nathanson K.L.
Identification of a novel subgroup of melanomas with KIT/cyclin-dependent kinase-4 overexpression.
Cancer Res. 68:5743-5752(2008)

Cross-references
Cell line collections (Providers) Rockland; WM858-01-0001
Cell line databases/resources cancercelllines; CVCL_C283
Encyclopedic resources Wikidata; Q54994326
Gene expression databases GEO; GSM109045
GEO; GSM186497
GEO; GSM186498
GEO; GSM952588
Polymorphism and mutation databases Cosmic; 1155558
Progenetix; CVCL_C283
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number23