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Cellosaurus WM853-2 (CVCL_C282)

[Text version]
Cell line name WM853-2
Synonyms WM-853-2; WM 853-2; WML 853-2
Accession CVCL_C282
Resource Identification Initiative To cite this cell line use: WM853-2 (RRID:CVCL_C282)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D8S1179: 11->11,14 and FGA: 22->20,22.
Derived from site: In situ; Back, skin; UBERON=UBERON_0001068.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 71Y
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133817,24
D3S135816,17
D5S81811,13
D7S82010,12
D8S117911,14
D13S31711,12
D16S53910,13
D18S5114
D19S43314,15
D21S1129,30
FGA20,22
TH019,9.3
TPOX8
vWA16,17

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=4053039
Herlyn M., Thurin J., Balaban-Malenbaum G.B., Bennicelli J.L., Herlyn D., Elder D.E., Bondi E., Guerry D. 4th, Nowell P.C., Clark W.H. Jr., Koprowski H.
Characteristics of cultured human melanocytes isolated from different stages of tumor progression.
Cancer Res. 45:5670-5676(1985)

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

Cross-references
Cell line collections (Providers) Rockland; WM853-2-01-0001
Cell line databases/resources cancercelllines; CVCL_C282
Encyclopedic resources Wikidata; Q54994324
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number19