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Cellosaurus WM3451 (CVCL_C273)

[Text version]
Cell line name WM3451
Synonyms WM-3451; WM 3451
Accession CVCL_C273
Resource Identification Initiative To cite this cell line use: WM3451 (RRID:CVCL_C273)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D19S433: 12,12.2->13,14 and D3S1358: 12,16->16,17.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_AP91 ! WM3456
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO12
D2S133820,26
D3S135816,17
D5S81812,13
D7S82010,11
D8S117913,15
D13S31710,11
D16S53910,11
D18S5112,13
D19S43313,14
D21S1129,30
FGA21,23
TH019.3
TPOX8,10
vWA18

Run an STR similarity search on this cell line
Web pages https://web.archive.org/web/20141129125241/http://www.wistar.org:80/lab/meenhard-herlyn-dvm-dsc/page/melanoma-cell-lines-0
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R., Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D., Dummer R.
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C273
Encyclopedic resources Wikidata; Q54994253
Gene expression databases GEO; GSM109039
GEO; GSM482483
GEO; GSM952598
Polymorphism and mutation databases Cosmic; 1303074
Progenetix; CVCL_C273
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number19