ID   WM3451
AC   CVCL_C273
SY   WM-3451; WM 3451
DR   cancercelllines; CVCL_C273
DR   Cosmic; 1303074
DR   GEO; GSM109039
DR   GEO; GSM482483
DR   GEO; GSM952598
DR   Progenetix; CVCL_C273
DR   Wikidata; Q54994253
RX   PubMed=16827748;
WW   https://web.archive.org/web/20141129125241/http://www.wistar.org:80/lab/meenhard-herlyn-dvm-dsc/page/melanoma-cell-lines-0
CC   Part of: Wistar Institute melanoma cell line collection.
CC   Sequence variation: Gene deletion; HGNC; 9588; PTEN; Zygosity=Homozygous (Wistar).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (Wistar).
CC   Omics: Transcriptome analysis by microarray.
CC   Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: D19S433: 12,12.2->13,14 and D3S1358: 12,16->16,17.
ST   Source(s): Wistar
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 10,11
ST   D16S539: 10,11
ST   D18S51: 12,13
ST   D19S433: 13,14
ST   D21S11: 29,30
ST   D2S1338: 20,26
ST   D3S1358: 16,17
ST   D5S818: 12,13
ST   D7S820: 10,11
ST   D8S1179: 13,15
ST   FGA: 21,23
ST   TH01: 9.3
ST   TPOX: 8,10
ST   vWA: 18
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_AP91 ! WM3456
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 05-10-23; Version: 18
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RX   PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x;
RA   Hoek K.S., Schlegel N.C., Brafford P., Sucker A., Ugurel S., Kumar R.,
RA   Weber B.L., Nathanson K.L., Phillips D.J., Herlyn M., Schadendorf D.,
RA   Dummer R.;
RT   "Metastatic potential of melanomas defined by specific gene expression
RT   profiles with no BRAF signature.";
RL   Pigment Cell Res. 19:290-302(2006).
//