Cellosaurus CI-hAELVi (CVCL_C1M0)
Cell line name | CI-hAELVi | ||||||||||||||||||||||||||||||||
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Synonyms | hAELVi.A; human Alveolar Epithelial Lentivirus immortalized clone A | ||||||||||||||||||||||||||||||||
Accession | CVCL_C1M0 | ||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: CI-hAELVi (RRID:CVCL_C1M0) | ||||||||||||||||||||||||||||||||
Comments | Characteristics: Suitable to model the air-blood barrier of the peripheral lung. Forms tight intercellular junctions, with high trans-epithelial electrical resistance (PubMed=26985677). Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=26985677). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC. Genetic integration: Method=Transduction; Gene=MGI; MGI:88138; Bcl2. Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299. Cell type: Type 1 pneumocyte; CL=CL_0002062. | ||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||
Hierarchy | Children:
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Originate from same individual | CVCL_C1M1 ! hAELVi.B | ||||||||||||||||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||||||||||||||||
Age at sampling | Age unspecified | ||||||||||||||||||||||||||||||||
Category | Transformed cell line | ||||||||||||||||||||||||||||||||
STR profile | Source(s): InSCREENeX=INS-CI-1015 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||
Web pages | Provider; InSCREENeX; INS-CI-1015; https://www.inscreenex.de/product/ci-haelvi/ | ||||||||||||||||||||||||||||||||
Publications | PubMed=26985677; DOI=10.14573/altex.1511131 PubMed=36748276; DOI=10.1002/advs.202207301; PMCID=PMC10015904 | ||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q114311559 | ||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||
Entry creation | 22-Sep-2022 | ||||||||||||||||||||||||||||||||
Last entry update | 10-Apr-2025 | ||||||||||||||||||||||||||||||||
Version number | 7 |