ID   hAELVi.A
AC   CVCL_C1M0
SY   human Alveolar Epithelial Lentivirus immortalized clone A
DR   Wikidata; Q114311559
RX   PubMed=26985677;
CC   Characteristics: Suitable to model the air-blood barrier of the peripheral lung. Forms tight intercellular junctions, with high trans-epithelial electrical resistance (PubMed=26985677).
CC   Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5361; ID2.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5362; ID3.
CC   Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:88138; Bcl2.
CC   Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
CC   Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299.
CC   Cell type: Type 1 pneumocyte; CL=CL_0002062.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_C1M1 ! hAELVi.B
SX   Sex unspecified
AG   Age unspecified
CA   Transformed cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=26985677; DOI=10.14573/altex.1511131;
RA   Kuehn A., Kletting S., de Souza Carvalho-Wodarz C., Repnik U.,
RA   Griffiths G.W., Fischer U., Meese E.U., Huwer H., Wirth D., May T.,
RA   Schneider-Daum N., Lehr C.-M.;
RT   "Human alveolar epithelial cells expressing tight junctions to model
RT   the air-blood barrier.";
RL   ALTEX 33:251-260(2016).
//