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Cellosaurus KKU-M214/246 (CVCL_C1L6)

[Text version]
Cell line name KKU-M214/246
Synonyms M214/246
Accession CVCL_C1L6
Resource Identification Initiative To cite this cell line use: KKU-M214/246 (RRID:CVCL_C1L6)
Comments Problematic cell line: Contaminated. Parent cell line (KKU-213B) shown to be a KKU-M213 derivative.
Population: Southeast Asian; Thai.
Selected for resistance to: ChEBI; CHEBI:46345; 5-fluorouracil (5-FU).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Cys (c.37G>T); ClinVar=VCV000045123; Zygosity=Unspecified (from parent cell line).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Opisthorchis viverrini-related cholangiocarcinoma (NCIt: C27769)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_M264 (KKU-213B)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=18714155; DOI=10.1159/000151541
Namwat N., Amimanan P., Loilome W., Jearanaikoon P., Sripa B., Bhudhisawasdi V., Tassaneeyakul W.
Characterization of 5-fluorouracil-resistant cholangiocarcinoma cell lines.
Chemotherapy 54:343-351(2008)

Cross-references
Encyclopedic resources Wikidata; Q114311820
Entry history
Entry creation22-Sep-2022
Last entry update29-Jun-2023
Version number4