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Cellosaurus betaG 40/110 (CVCL_C1JZ)

[Text version]
Cell line name betaG 40/110
Synonyms betaG40/110; BG 40/110
Accession CVCL_C1JZ
Resource Identification Initiative To cite this cell line use: betaG 40/110 (RRID:CVCL_C1JZ)
Comments Characteristics: Transfected with both a pCB6-INS-Neo and a PCB7-GK-HygroR constructs (PubMed=9166666).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6081; INS.
Genetic integration: Method=Transfection; Gene=RGD; 2670; Gck.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS:0000603.
Hierarchy Parent: CVCL_C1JU (betaG I/17)
Sex of cell Male
Age at sampling 666D
Category Cancer cell line
Publications

PubMed=9166666; DOI=10.2337/diab.46.6.958
Clark S.A., Quaade C., Constandy H., Hansen P., Halban P.A., Ferber S., Newgard C.B., Normington K.
Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression.
Diabetes 46:958-967(1997)

PubMed=9166667; DOI=10.2337/diab.46.6.968
Hohmeier H.-E., BeltrandelRio H., Clark S.A., Henkel-Rieger R., Normington K., Newgard C.B.
Regulation of insulin secretion from novel engineered insulinoma cell lines.
Diabetes 46:968-977(1997)

Cross-references
Encyclopedic resources Wikidata; Q114310744
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number7