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Cellosaurus betaG 23/21 (CVCL_C1JW)

[Text version]
Cell line name betaG 23/21
Synonyms betaG23/21
Accession CVCL_C1JW
Resource Identification Initiative To cite this cell line use: betaG 23/21 (RRID:CVCL_C1JW)
Comments Characteristics: Transfected with both a pCB6-INS-Neo and a pCMV8-GK-IRES-GPT constructs (PubMed=9166666).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6081; INS.
Genetic integration: Method=Transfection; Gene=RGD; 2670; Gck.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P0A9M5; Escherichia coli gpt.
Transformant: NCIt; C17262; X-Ray.
Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006.
Cell type: Pancreatic beta cell; CL=CL_0000169.
Disease Rat insulinoma (NCIt: C121566)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS:0000603.
Hierarchy Parent: CVCL_C1JU (betaG I/17)
Children:
CVCL_C1JY (betaG 49/206)
Sex of cell Male
Age at sampling 666D
Category Cancer cell line
Publications

PubMed=9166666; DOI=10.2337/diab.46.6.958
Clark S.A., Quaade C., Constandy H., Hansen P., Halban P.A., Ferber S., Newgard C.B., Normington K.
Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression.
Diabetes 46:958-967(1997)

Cross-references
Encyclopedic resources Wikidata; Q114310742
Entry history
Entry creation22-Sep-2022
Last entry update19-Dec-2024
Version number6