Cellosaurus betaG 111/228 (CVCL_C1JL)
| Cell line name | betaG 111/228 |
|---|---|
| Synonyms | betaG111/228 |
| Accession | CVCL_C1JL |
| Resource Identification Initiative | To cite this cell line use: betaG 111/228 (RRID:CVCL_C1JL) |
| Comments | Characteristics: Transfected with both a pCMV8-INS-IRES-Neo and a pCMV8-INS-IRES-PuroR constructs. Expresses 60 times more insulin than the grand-parent cell line (PubMed=9166666). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6081; INS. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCIt; C17262; X-Ray. Derived from site: In situ; Pancreas, islets of Langerhans; UBERON=UBERON_0000006. Cell type: Pancreatic beta cell; CL=CL_0000169. |
| Disease | Rat insulinoma (NCIt: C121566) |
| Species of origin | Rattus norvegicus (Rat)
(NCBI Taxonomy: 10116)
Breed/subspecies: NEDH; RS=RS:0000603. |
| Hierarchy | Parent: CVCL_C1JK (betaG 18/3E1) |
| Sex of cell | Male |
| Age at sampling | 666D |
| Category | Cancer cell line |
| Publications | PubMed=9166666; DOI=10.2337/diab.46.6.958 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q114310740 |
| Entry history | |
| Entry creation | 22-Sep-2022 |
| Last entry update | 19-Dec-2024 |
| Version number | 6 |