Cellosaurus BEL-A 5x KO (CVCL_C0XI)
| Cell line name | BEL-A 5x KO |
|---|---|
| Synonyms | 5x KO BEL-A; 5x KO #4 BEL-A |
| Accession | CVCL_C0XI |
| Resource Identification Initiative | To cite this cell line use: BEL-A 5x KO (RRID:CVCL_C0XI) |
| Comments | Characteristics: Completely deficient in blood groups encoded by five different genes that encode antigens responsible for the most common transfusion incompatibilities. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4035; ACKR1. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4012; FUT1. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4703; GYPB. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:6308; KEL. Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:10006; RHAG. Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Omics: Deep quantitative proteome analysis. Omics: Genome sequenced. Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371. Cell type: Mononuclear cell; CL=CL_0000842. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_C0XH (BEL-A 4x KO) |
| Sex of cell | Sex unspecified |
| Age at sampling | Adult |
| Category | Transformed cell line |
| Publications | PubMed=29700043; DOI=10.15252/emmm.201708454; PMCID=PMC5991592 CLPUB00710 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q114310729 |
| Proteomic databases | PRIDE; PXD009291 |
| Entry history | |
| Entry creation | 22-Sep-2022 |
| Last entry update | 19-Dec-2024 |
| Version number | 7 |