Cellosaurus cell line 1-11 (CVCL

Cellosaurus 1-11 (CVCL_C0WE)

Cross-references
Cell line name	1-11
Accession	CVCL_C0WE
Resource Identification Initiative	To cite this cell line use: 1-11 (RRID:CVCL_C0WE)
Comments	Characteristics: Derived from a progenitor/stem cell present in the periodontal ligament and may be very useful for studying the biology and regeneration of periodontium (PubMed=18181171). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo). Derived from site: In situ; Tooth, periodontal ligament; UBERON=UBERON_0008266. Cell type: Fibroblast of periodontal ligament; CL=CL_2000017.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_C0WC (STPLF-fF)
Sex of cell	Female
Age at sampling	20Y
Category	Transformed cell line
Publications	PubMed=18021259; DOI=10.1111/j.1432-0436.2007.00233.x Tomokiyo A., Maeda H., Fujii S., Wada N., Shima K., Akamine A. Development of a multipotent clonal human periodontal ligament cell line. Differentiation 76:337-347(2008) PubMed=18181171; DOI=10.1002/jcp.21359 Fujii S., Maeda H., Wada N., Tomokiyo A., Saito M., Akamine A. Investigating a clonal human periodontal ligament progenitor/stem cell line in vitro and in vivo. J. Cell. Physiol. 215:743-749(2008) PubMed=20931341; DOI=10.1007/s00441-010-1037-x Fujii S., Maeda H., Tomokiyo A., Monnouchi S., Hori K., Wada N., Akamine A. Effects of TGF-beta1 on the proliferation and differentiation of human periodontal ligament cells and a human periodontal ligament stem/progenitor cell line. Cell Tissue Res. 342:233-242(2010)
Encyclopedic resources	Wikidata; Q114245350
Entry history
Entry creation	22-Sep-2022
Last entry update	19-Dec-2024
Version number	6