ID   1-11
AC   CVCL_C0WE
DR   Wikidata; Q114245350
RX   PubMed=18021259;
RX   PubMed=18181171;
RX   PubMed=20931341;
CC   Characteristics: Derived from a progenitor/stem cell present in the periodontal ligament and may be very useful for studying the biology and regeneration of periodontium (PubMed=18181171).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:11730; TERT.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
CC   Derived from site: In situ; Tooth, periodontal ligament; UBERON=UBERON_0008266.
CC   Cell type: Fibroblast of periodontal ligament; CL=CL_2000017.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_C0WC ! STPLF-fF
SX   Female
AG   20Y
CA   Transformed cell line
DT   Created: 22-09-22; Last updated: 19-12-24; Version: 6
//
RX   PubMed=18021259; DOI=10.1111/j.1432-0436.2007.00233.x;
RA   Tomokiyo A., Maeda H., Fujii S., Wada N., Shima K., Akamine A.;
RT   "Development of a multipotent clonal human periodontal ligament cell
RT   line.";
RL   Differentiation 76:337-347(2008).
//
RX   PubMed=18181171; DOI=10.1002/jcp.21359;
RA   Fujii S., Maeda H., Wada N., Tomokiyo A., Saito M., Akamine A.;
RT   "Investigating a clonal human periodontal ligament progenitor/stem
RT   cell line in vitro and in vivo.";
RL   J. Cell. Physiol. 215:743-749(2008).
//
RX   PubMed=20931341; DOI=10.1007/s00441-010-1037-x;
RA   Fujii S., Maeda H., Tomokiyo A., Monnouchi S., Hori K., Wada N.,
RA   Akamine A.;
RT   "Effects of TGF-beta1 on the proliferation and differentiation of
RT   human periodontal ligament cells and a human periodontal ligament
RT   stem/progenitor cell line.";
RL   Cell Tissue Res. 342:233-242(2010).
//