| Cell line name |
KE37/1-IIIB |
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| Accession |
CVCL_C0UC |
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| Resource Identification Initiative |
To cite this cell line use: KE37/1-IIIB (RRID:CVCL_C0UC) |
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| Comments |
Population: Caucasian.
Virology: Latently infected with HIV-1 isolate LAI. |
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| Sequence variations |
- Mutation; HGNC; 7881; NOTCH1; Simple; p.Gln2459Ter (c.7375C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9585; PTCH1; Simple; p.Arg571Gln (c.1712G>A); ClinVar=VCV000819886; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 9884; RB1; Simple; p.Gly310Glu (c.929G>A); ClinVar=VCV000237678; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; 11998; TP53; Simple; p.Pro153Alafs*28 (c.455dupC) (c.455_456insC) (p.P152fs) (c.459_460insC); ClinVar=VCV000182958; Zygosity=Heterozygous (from parent cell line).
|
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| Disease |
Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_B7RK (KE37/1) |
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| Sex of cell |
Male |
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| Age at sampling |
27Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=1373627; DOI=10.1097/00002030-199203000-00004
Brack-Werner R., Kleinschmidt A., Ludvigsen A., Mellert W., Neumann M., Herrmann R., Khim M.C.L., Burny A., Muller-Lantzsch N., Stavrou D., Erfle V.
Infection of human brain cells by HIV-1: restricted virus production in chronically infected human glial cell lines.
AIDS 6:273-285(1992) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_C0UC
|
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| Encyclopedic resources |
Wikidata; Q112929943
|
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| Entry history |
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| Entry creation | 23-Jun-2022 |
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| Last entry update | 05-Oct-2023 |
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| Version number | 5 |
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