Cellosaurus logo
expasy logo
Due to maintenance work, this service will be unavailable from Mon Nov 11 17:30 until Tue Nov 12 09:00 CET. Apologies for the inconvenience.

Cellosaurus KE37/1-IIIB (CVCL_C0UC)

[Text version]
Cell line name KE37/1-IIIB
Accession CVCL_C0UC
Resource Identification Initiative To cite this cell line use: KE37/1-IIIB (RRID:CVCL_C0UC)
Comments Population: Caucasian.
Virology: Latently infected with HIV-1 isolate LAI.
Sequence variations
  • Mutation; HGNC; 7881; NOTCH1; Simple; p.Gln2459Ter (c.7375C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9585; PTCH1; Simple; p.Arg571Gln (c.1712G>A); ClinVar=VCV000819886; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Simple; p.Gly310Glu (c.929G>A); ClinVar=VCV000237678; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Pro153Alafs*28 (c.455dupC) (c.455_456insC) (p.P152fs) (c.459_460insC); ClinVar=VCV000182958; Zygosity=Heterozygous (from parent cell line).
Disease Adult T acute lymphoblastic leukemia (NCIt: C9142)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_B7RK (KE37/1)
Sex of cell Male
Age at sampling 27Y
Category Cancer cell line
Publications

PubMed=1373627; DOI=10.1097/00002030-199203000-00004
Brack-Werner R., Kleinschmidt A., Ludvigsen A., Mellert W., Neumann M., Herrmann R., Khim M.C.-L., Burny A., Muller-Lantzsch N., Stavrou D., Erfle V.
Infection of human brain cells by HIV-1: restricted virus production in chronically infected human glial cell lines.
AIDS 6:273-285(1992)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C0UC
Encyclopedic resources Wikidata; Q112929943
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5