ID   KE37/1-IIIB
AC   CVCL_C0UC
DR   cancercelllines; CVCL_C0UC
DR   Wikidata; Q112929943
RX   PubMed=1373627;
CC   Population: Caucasian.
CC   Virology: Latently infected with HIV-1 isolate LAI.
CC   Sequence variation: Mutation; HGNC; 7881; NOTCH1; Simple; p.Gln2459Ter (c.7375C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9585; PTCH1; Simple; p.Arg571Gln (c.1712G>A); ClinVar=VCV000819886; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 9884; RB1; Simple; p.Gly310Glu (c.929G>A); ClinVar=VCV000237678; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Pro153Alafs*28 (c.455dupC) (c.455_456insC) (p.P152fs) (c.459_460insC); ClinVar=VCV000182958; Zygosity=Heterozygous (from parent cell line).
DI   NCIt; C9142; Adult T acute lymphoblastic leukemia
DI   ORDO; Orphanet_99861; Precursor T-cell acute lymphoblastic leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_B7RK ! KE37/1
SX   Male
AG   27Y
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 05-10-23; Version: 5
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RX   PubMed=1373627; DOI=10.1097/00002030-199203000-00004;
RA   Brack-Werner R., Kleinschmidt A., Ludvigsen A., Mellert W.,
RA   Neumann M., Herrmann R., Khim M.C.-L., Burny A., Muller-Lantzsch N.,
RA   Stavrou D., Erfle V.;
RT   "Infection of human brain cells by HIV-1: restricted virus production
RT   in chronically infected human glial cell lines.";
RL   AIDS 6:273-285(1992).
//