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Cellosaurus SiHa-APOA1 (CVCL_C0TY)

[Text version]
Cell line name SiHa-APOA1
Accession CVCL_C0TY
Resource Identification Initiative To cite this cell line use: SiHa-APOA1 (RRID:CVCL_C0TY)
Comments Population: Japanese.
Virology: Contains a complete HPV16 genome with a disruption of the E2 region and a small deletion (from parent cell line).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:600; APOA1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical squamous cell carcinoma (NCIt: C27676)
Squamous cell carcinoma of the cervix uteri (ORDO: Orphanet_213767)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0032 (SiHa)
Sex of cell Female
Age at sampling 55Y
Category Cancer cell line
Publications

PubMed=35421932; DOI=10.1186/s12885-022-09528-x; PMCID=PMC9009492
He Y., Han S.-B., Liu Y., Zhang J.-J., Wu Y.-M.
Role of APOA1 in the resistance to platinum-based chemotherapy in squamous cervical cancer.
BMC Cancer 22:411.1-411.12(2022)

Cross-references
Encyclopedic resources Wikidata; Q112930391
Proteomic databases PRIDE; PXD030885
Entry history
Entry creation23-Jun-2022
Last entry update19-Dec-2024
Version number7