Cellosaurus HUDEP2 HBB-KO (CVCL_C0QM)
| Cell line name | HUDEP2 HBB-KO |
|---|---|
| Accession | CVCL_C0QM |
| Resource Identification Initiative | To cite this cell line use: HUDEP2 HBB-KO (RRID:CVCL_C0QM) |
| Comments | Population: Japanese. Characteristics: Expression of the HPV16 E6 and E7 genes is induced by tetracycline (from parent cell line). Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4827; HBB. Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6. Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Omics: Chromatin accessibility by ATAC-seq. Omics: Deep quantitative proteome analysis. Omics: Transcriptome analysis by RNAseq. Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168. Cell type: Erythroid progenitor cell; CL=CL_0000038. |
| Disease | Sickle cell disease (NCIt: C34383) Sickle cell anemia (ORDO: Orphanet_232) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_VI06 (HUDEP-2) |
| Sex of cell | Sex unspecified |
| Age at sampling | <1D |
| Category | Transformed cell line |
| Publications | PubMed=35269949; DOI=10.3390/ijms23052807; PMCID=PMC8911073 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q112929794 |
| Proteomic databases | PRIDE; PXD030182 |
| Entry history | |
| Entry creation | 23-Jun-2022 |
| Last entry update | 19-Dec-2024 |
| Version number | 7 |