Cellosaurus logo
expasy logo

Cellosaurus UPCI-SCC-003 (CVCL_C025)

[Text version]
Cell line name UPCI-SCC-003
Synonyms UPCI:SCC003; UPCISCC003; SCC003
Accession CVCL_C025
Resource Identification Initiative To cite this cell line use: UPCI-SCC-003 (RRID:CVCL_C025)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Doubling time: ~45 hours (DSMZ=ACC-863).
Omics: DNA methylation analysis.
Omics: Protein expression by reverse-phase protein arrays.
Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
Disease Tonsillar squamous cell carcinoma (NCIt: C8183)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 65Y
Category Cancer cell line
STR profile Source(s): DSMZ

Markers:
AmelogeninX
CSF1PO11
D2S133820
D3S135814
D5S81811
D7S8208,14
D8S11798
D13S31711
D16S5399
D18S5113
D19S43314
D21S1129,30
FGA25
Penta D11,13
Penta E12
TH018,9
TPOX8,11
vWA17,18

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001
White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L., Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T., Gollin S.M.
The influence of clinical and demographic risk factors on the establishment of head and neck squamous cell carcinoma cell lines.
Oral Oncol. 43:701-712(2007)

PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003
Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W., Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.
Chromosomal imbalances in oral squamous cell carcinoma: examination of 31 cell lines and review of the literature.
Oral Oncol. 44:369-382(2008)

PubMed=23419152; DOI=10.1186/gm419
Lechner M., Fenton T., West J., Wilson G., Feber A., Henderson S., Thirlwell C., Dibra H.K., Jay A., Butcher L.M., Chakravarthy A.R., Gratrix F., Patel N., Vaz F., O'Flynn P., Kalavrezos N., Teschendorff A.E., Boshoff C., Beck S.
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Genome Med. 5:15.1-15.16(2013)

PubMed=24403267; DOI=10.1002/cam4.151
Kawakami H., Okamoto I., Terao K., Sakai K., Suzuki M., Ueda S., Tanaka K., Kuwata K., Morita Y., Ono K., Nishio K., Nishimura Y., Doi K., Nakagawa K.
Human papillomavirus DNA and p16 expression in Japanese patients with oropharyngeal squamous cell carcinoma.
Cancer Med. 2:933-941(2013)

PubMed=24142626; DOI=10.1002/gcc.22115
Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W., Vlad A., Gollin S.M.
Upregulation of the ATR-CHEK1 pathway in oral squamous cell carcinomas.
Genes Chromosomes Cancer 53:25-37(2014)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) DSMZ; ACC-863
Cell line databases/resources DSMZCellDive; ACC-863
Encyclopedic resources Wikidata; Q54991560
Gene expression databases GEO; GSM937836
GEO; GSM937837
Entry history
Entry creation06-Jun-2012
Last entry update29-Jun-2023
Version number12