ID   UPCI-SCC-003
AC   CVCL_C025
SY   UPCI:SCC003; UPCISCC003; SCC003
DR   DSMZ; ACC-863
DR   DSMZCellDive; ACC-863
DR   GEO; GSM937836
DR   GEO; GSM937837
DR   Wikidata; Q54991560
RX   PubMed=17112776;
RX   PubMed=17681875;
RX   PubMed=23419152;
RX   PubMed=24142626;
RX   PubMed=24403267;
RX   PubMed=28196595;
WW   https://tcpaportal.org/mclp/
CC   Part of: MD Anderson Cell Lines Project.
CC   Population: Caucasian.
CC   Doubling time: ~45 hours (DSMZ=ACC-863).
CC   Omics: DNA methylation analysis.
CC   Omics: Protein expression by reverse-phase protein arrays.
CC   Derived from site: In situ; Oral cavity, tonsil; UBERON=UBERON_0002372.
ST   Source(s): DSMZ
ST   Amelogenin: X
ST   CSF1PO: 11
ST   D13S317: 11
ST   D16S539: 9
ST   D18S51: 13
ST   D19S433: 14
ST   D21S11: 29,30
ST   D2S1338: 20
ST   D3S1358: 14
ST   D5S818: 11
ST   D7S820: 8,14
ST   D8S1179: 8
ST   FGA: 25
ST   Penta D: 11,13
ST   Penta E: 12
ST   TH01: 8,9
ST   TPOX: 8,11
ST   vWA: 17,18
DI   NCIt; C8183; Tonsillar squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   65Y
CA   Cancer cell line
DT   Created: 06-06-12; Last updated: 29-06-23; Version: 12
//
RX   PubMed=17112776; DOI=10.1016/j.oraloncology.2006.09.001;
RA   White J.S., Weissfeld J.L., Ragin C.C.R., Rossie K.M., Martin C.L.,
RA   Shuster M., Ishwad C.S., Law J.C., Myers E.N., Johnson J.T.,
RA   Gollin S.M.;
RT   "The influence of clinical and demographic risk factors on the
RT   establishment of head and neck squamous cell carcinoma cell lines.";
RL   Oral Oncol. 43:701-712(2007).
//
RX   PubMed=17681875; DOI=10.1016/j.oraloncology.2007.05.003;
RA   Martin C.L., Reshmi S.C., Ried T., Gottberg W., Wilson J.W.,
RA   Reddy J.K., Khanna P., Johnson J.T., Myers E.N., Gollin S.M.;
RT   "Chromosomal imbalances in oral squamous cell carcinoma: examination
RT   of 31 cell lines and review of the literature.";
RL   Oral Oncol. 44:369-382(2008).
//
RX   PubMed=23419152; DOI=10.1186/gm419;
RA   Lechner M., Fenton T., West J., Wilson G., Feber A., Henderson S.,
RA   Thirlwell C., Dibra H.K., Jay A., Butcher L.M., Chakravarthy A.R.,
RA   Gratrix F., Patel N., Vaz F., O'Flynn P., Kalavrezos N.,
RA   Teschendorff A.E., Boshoff C., Beck S.;
RT   "Identification and functional validation of HPV-mediated
RT   hypermethylation in head and neck squamous cell carcinoma.";
RL   Genome Med. 5:15.1-15.16(2013).
//
RX   PubMed=24142626; DOI=10.1002/gcc.22115;
RA   Parikh R.A., Appleman L.J., Bauman J.E., Sankunny M., Lewis D.W.,
RA   Vlad A., Gollin S.M.;
RT   "Upregulation of the ATR-CHEK1 pathway in oral squamous cell
RT   carcinomas.";
RL   Genes Chromosomes Cancer 53:25-37(2014).
//
RX   PubMed=24403267; DOI=10.1002/cam4.151;
RA   Kawakami H., Okamoto I., Terao K., Sakai K., Suzuki M., Ueda S.,
RA   Tanaka K., Kuwata K., Morita Y., Ono K., Nishio K., Nishimura Y.,
RA   Doi K., Nakagawa K.;
RT   "Human papillomavirus DNA and p16 expression in Japanese patients with
RT   oropharyngeal squamous cell carcinoma.";
RL   Cancer Med. 2:933-941(2013).
//
RX   PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005;
RA   Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P.,
RA   Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L.,
RA   Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D.,
RA   Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B.,
RA   Liang H.;
RT   "Characterization of human cancer cell lines by reverse-phase protein
RT   arrays.";
RL   Cancer Cell 31:225-239(2017).
//