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Cellosaurus SK/IFN-gamma (CVCL_B7TE)

[Text version]
Cell line name SK/IFN-gamma
Accession CVCL_B7TE
Resource Identification Initiative To cite this cell line use: SK/IFN-gamma (RRID:CVCL_B7TE)
Comments Population: Caucasian.
Characteristics: Intermediate type (I-type) (from parent cell line).
Characteristics: MYCN-amplified NBL cell line (from parent cell line).
Genetic integration: Method=Transfection; Gene=HGNC; 5438; IFNG.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: Metastatic; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene deletion; HGNC; 11998; TP53; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Cys135Phe (c.404G>T); ClinVar=VCV000376559; Zygosity=Heterozygous (from parent cell line).
Disease Neuroblastoma (NCIt: C3270)
Neuroblastoma (ORDO: Orphanet_635)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0529 (SK-N-BE(2)-C)
Sex of cell Male
Age at sampling 2Y2M
Category Cancer cell line
Publications

PubMed=15150552; DOI=10.1038/sj.bjc.6601842; PMCID=PMC2409504
Airoldi I., Meazza R., Croce M., Di Carlo E., Piazza T., Cocco C., D'Antuono T., Pistoia V., Ferrini S., Corrias M.V.
Low-dose interferon-gamma-producing human neuroblastoma cells show reduced proliferation and delayed tumorigenicity.
Br. J. Cancer 90:2210-2218(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B7TE
Encyclopedic resources Wikidata; Q112930406
Entry history
Entry creation23-Jun-2022
Last entry update10-Sep-2024
Version number6