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Cellosaurus Su9T01 (CVCL_B7P5)

[Text version]
Cell line name Su9T01
Synonyms SU9T01
Accession CVCL_B7P5
Resource Identification Initiative To cite this cell line use: Su9T01 (RRID:CVCL_B7P5)
Comments Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Adult T-cell leukemia/lymphoma (NCIt: C3184)
Adult T-cell leukemia/lymphoma (ORDO: Orphanet_86875)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=1719236; DOI=10.1128/JVI.65.12.6892-6899.1991; PMCID=PMC250789
Arima N., Molitor J.A., Smith M.R., Kim J.H., Daitoku Y., Greene W.C.
Human T-cell leukemia virus type I Tax induces expression of the Rel-related family of kappa B enhancer-binding proteins: evidence for a pretranslational component of regulation.
J. Virol. 65:6892-6899(1991)

PubMed=1472476; DOI=10.1093/intimm/4.11.1233
Mills G.B., Arima N., May C., Hill M., Schmandt R., Li J., Miyamoto N.G., Greene W.C.
Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated signal transduction in HTLV-I-infected human T cells.
Int. Immunol. 4:1233-1243(1992)

PubMed=9357968
Ohtsubo H., Arima N., Matsushita K., Hidaka S., Fujiwara H., Arimura K., Kukita T., Fukumori J., Matsumoto T., Eizuru Y., Tanaka H.
Human T lymphotropic virus-type I Tax induction of CD21/Epstein-Barr virus receptor expression on T cells and its significance in leukemogenesis of adult T cell leukemia.
Exp. Hematol. 25:1246-1252(1997)

PubMed=34794206; DOI=10.1111/cas.15204; PMCID=PMC8819293
Ikebe E., Shimosaki S., Hasegawa H., Iha H., Tsukamoto Y., Wang Y., Sasaki D., Imaizumi Y., Miyazaki Y., Yanagihara K., Hamaguchi I., Morishita K.
TAS-116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T-cell leukemia.
Cancer Sci. 113:684-696(2022)

Cross-references
Encyclopedic resources Wikidata; Q112930433
Gene expression databases GEO; GSE168558
Entry history
Entry creation23-Jun-2022
Last entry update29-Jun-2023
Version number4