ID   Su9T01
AC   CVCL_B7P5
SY   SU9T01
DR   GEO; GSE168558
DR   Wikidata; Q112930433
RX   PubMed=1472476;
RX   PubMed=1719236;
RX   PubMed=9357968;
RX   PubMed=34794206;
CC   Characteristics: IL2 dependent.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Omics: Transcriptome analysis by microarray.
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C3184; Adult T-cell leukemia/lymphoma
DI   ORDO; Orphanet_86875; Adult T-cell leukemia/lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
AG   Adult
CA   Cancer cell line
DT   Created: 23-06-22; Last updated: 29-06-23; Version: 4
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RX   PubMed=1472476; DOI=10.1093/intimm/4.11.1233;
RA   Mills G.B., Arima N., May C., Hill M., Schmandt R., Li J.,
RA   Miyamoto N.G., Greene W.C.;
RT   "Neither the LCK nor the FYN kinases are obligatory for IL-2-mediated
RT   signal transduction in HTLV-I-infected human T cells.";
RL   Int. Immunol. 4:1233-1243(1992).
//
RX   PubMed=1719236; DOI=10.1128/JVI.65.12.6892-6899.1991; PMCID=PMC250789;
RA   Arima N., Molitor J.A., Smith M.R., Kim J.H., Daitoku Y., Greene W.C.;
RT   "Human T-cell leukemia virus type I Tax induces expression of the
RT   Rel-related family of kappa B enhancer-binding proteins: evidence for
RT   a pretranslational component of regulation.";
RL   J. Virol. 65:6892-6899(1991).
//
RX   PubMed=9357968;
RA   Ohtsubo H., Arima N., Matsushita K., Hidaka S., Fujiwara H.,
RA   Arimura K., Kukita T., Fukumori J., Matsumoto T., Eizuru Y.,
RA   Tanaka H.;
RT   "Human T lymphotropic virus-type I Tax induction of CD21/Epstein-Barr
RT   virus receptor expression on T cells and its significance in
RT   leukemogenesis of adult T cell leukemia.";
RL   Exp. Hematol. 25:1246-1252(1997).
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RX   PubMed=34794206; DOI=10.1111/cas.15204; PMCID=PMC8819293;
RA   Ikebe E., Shimosaki S., Hasegawa H., Iha H., Tsukamoto Y., Wang Y.,
RA   Sasaki D., Imaizumi Y., Miyazaki Y., Yanagihara K., Hamaguchi I.,
RA   Morishita K.;
RT   "TAS-116 (pimitespib), a heat shock protein 90 inhibitor, shows
RT   efficacy in preclinical models of adult T-cell leukemia.";
RL   Cancer Sci. 113:684-696(2022).
//