Cellosaurus logo
expasy logo

Cellosaurus HEp-2/VCR (CVCL_B7H7)

[Text version]
Cell line name HEp-2/VCR
Accession CVCL_B7H7
Resource Identification Initiative To cite this cell line use: HEp-2/VCR (RRID:CVCL_B7H7)
Comments Problematic cell line: Contaminated. Parent cell line (HEp-2) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI:28445; Vincristine (VCR).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1906 (HEp-2)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=29483928; DOI=10.1186/s11658-017-0067-8
Li G.-D., Hu X.-L., Sun L., Li X., Li J.-F., Li T.-L., Zhang X.-H.
C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance.
Cell. Mol. Biol. Lett. 23:6.1-6.12(2018)

Encyclopedic resources Wikidata; Q112929711
Entry history
Entry creation23-Jun-2022
Last entry update05-Oct-2023
Version number5