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Cellosaurus U-2 OS-ZFN-SNAP-Nup107 no.294 (CVCL_B7FM)

[Text version]
Cell line name U-2 OS-ZFN-SNAP-Nup107 no.294
Accession CVCL_B7FM
Resource Identification Initiative To cite this cell line use: U-2 OS-ZFN-SNAP-Nup107 no.294 (RRID:CVCL_B7FM)
Comments Population: Caucasian.
Characteristics: Using ZFN NUP107 has been endogenously tagged in both alleles at the N-terminus with a SNAP-tag (PubMed=29630062).
Genetic integration: Method=ZFN; Gene=HGNC; 7059; MGMT (Note=With p.Gly180_Asn_207del and 19 mutations = SNAP-tag).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=29630062; DOI=10.1038/nmeth.4661; PMCID=PMC6009849
Li Y.-M., Mund M., Hoess P., Deschamps J., Matti U., Nijmeijer-Winter B., Sabinina V.J., Ellenberg J., Schoen I., Ries J.
Real-time 3D single-molecule localization using experimental point spread functions.
Nat. Methods 15:367-369(2018)

Cross-references
Cell line collections (Providers) CLS; 300294
Encyclopedic resources Wikidata; Q112930493
Entry history
Entry creation23-Jun-2022
Last entry update10-Sep-2024
Version number6