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Cellosaurus ZX2021H (CVCL_B6ZD)

[Text version]
Cell line name ZX2021H
Synonyms TJYK-ZLL-01
Accession CVCL_B6ZD
Resource Identification Initiative To cite this cell line use: ZX2021H (RRID:CVCL_B6ZD)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2021215.
Population: Chinese.
Doubling time: ~29.8 hours (PubMed=35297208).
Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; 1097; BRAF; Simple; p.Asp22Asn (c.64G>A); ClinVar=VCV000040335; Zygosity=Unspecified (PubMed=35297208).
  • Mutation; HGNC; 7765; NF1; Simple; p.Cys2134Tyrfs*8 (c.6401_6402delGT) (p.L2133fs, c.6398_6399del); ClinVar=VCV000818199; Zygosity=Unspecified (PubMed=35297208).
  • Mutation; HGNC; 11998; TP53; Simple; p.His179Arg (c.536A>G); ClinVar=VCV000376606; Zygosity=Unspecified (PubMed=35297208).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 42Y
Category Cancer cell line
STR profile Source(s): Patent=CN113817684A; PubMed=35297208

Markers:
AmelogeninX
CSF1PO12
D2S44110
D2S133819
D3S135816
D5S8189
D6S104314
D7S8208,12
D8S117913
D12S39120
D13S3179,11
D16S5399,12
D18S5114,16
D19S43313,15.2
D21S1131
FGA19,21
Penta D12
Penta E13
TH017,9
TPOX8
vWA17

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Publications

Patent=CN113817684A
Xu S., Zu L.-L., He J.-L., Zhu S., Zhou N., Jin X., Yang L.-Q., Zhu Y.-F., Lei X.
Chinese lung adenocarcinoma cell line with high lymph node metastasis potential and application thereof.
Patent number CN113817684A, 21-Dec-2021

PubMed=35297208; DOI=10.1111/1759-7714.14385
Zu L.-L., Li X.-B., He J.-L., Zhou N., Meng F.-R., Li X.-Z., Xu S., Zhang L.
Establishment and characterization of a novel highly malignant lung cancer cell line ZX2021H derived from a metastatic lymph node lesion.
Thorac. Cancer 13:1199-1210(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6ZD
CCRID; 4201PAT-CCTCC01828
Encyclopedic resources Wikidata; Q112041948
Entry history
Entry creation17-Mar-2022
Last entry update05-Oct-2023
Version number6