ID   ZX2021H
AC   CVCL_B6ZD
SY   TJYK-ZLL-01
DR   cancercelllines; CVCL_B6ZD
DR   CCRID; 4201PAT-CCTCC01828
DR   Wikidata; Q112041948
RX   Patent=CN113817684A;
RX   PubMed=35297208;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C2021215.
CC   Population: Chinese.
CC   Doubling time: ~29.8 hours (PubMed=35297208).
CC   Sequence variation: Mutation; HGNC; 1097; BRAF; Simple; p.Asp22Asn (c.64G>A); ClinVar=VCV000040335; Zygosity=Unspecified (PubMed=35297208).
CC   Sequence variation: Mutation; HGNC; 7765; NF1; Simple; p.Cys2134Tyrfs*8 (c.6401_6402delGT) (p.L2133fs, c.6398_6399del); ClinVar=VCV000818199; Zygosity=Unspecified (PubMed=35297208).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.His179Arg (c.536A>G); ClinVar=VCV000376606; Zygosity=Unspecified (PubMed=35297208).
CC   Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
ST   Source(s): Patent=CN113817684A; PubMed=35297208
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D12S391: 20
ST   D13S317: 9,11
ST   D16S539: 9,12
ST   D18S51: 14,16
ST   D19S433: 13,15.2
ST   D21S11: 31
ST   D2S1338: 19
ST   D2S441: 10
ST   D3S1358: 16
ST   D5S818: 9
ST   D6S1043: 14
ST   D7S820: 8,12
ST   D8S1179: 13
ST   FGA: 19,21
ST   Penta D: 12
ST   Penta E: 13
ST   TH01: 7,9
ST   TPOX: 8
ST   vWA: 17
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   42Y
CA   Cancer cell line
DT   Created: 17-03-22; Last updated: 05-10-23; Version: 6
//
RX   Patent=CN113817684A;
RA   Xu S., Zu L.-L., He J.-L., Zhu S., Zhou N., Jin X., Yang L.-Q.,
RA   Zhu Y.-F., Lei X.;
RT   "Chinese lung adenocarcinoma cell line with high lymph node metastasis
RT   potential and application thereof.";
RL   Patent number CN113817684A, 21-Dec-2021.
//
RX   PubMed=35297208; DOI=10.1111/1759-7714.14385;
RA   Zu L.-L., Li X.-B., He J.-L., Zhou N., Meng F.-R., Li X.-Z., Xu S.,
RA   Zhang L.;
RT   "Establishment and characterization of a novel highly malignant lung
RT   cancer cell line ZX2021H derived from a metastatic lymph node
RT   lesion.";
RL   Thorac. Cancer 13:1199-1210(2022).
//