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Cellosaurus Aag2INF (CVCL_B6Y7)

[Text version]
Cell line name Aag2INF
Synonyms Aag2(INF)
Accession CVCL_B6Y7
Resource Identification Initiative To cite this cell line use: Aag2INF (RRID:CVCL_B6Y7)
Comments Group: Insect cell line.
Virology: Persistently infected by Chikungunya virus and Mayaro virus (PubMed=34878970).
Virology: The Chikungunya virus in this cell line has accumulated non-synonymous mutations and encodes a shorter nsP3 gene and has lost the capacity to infect mammalian cells (PubMed=34878970).
Anecdotal: Was accidentally created by a student that was working with Aag-2 and also manipulating samples containing arboviruses.
Species of origin Aedes aegypti (Yellowfever mosquito) (Culex aegypti) (NCBI Taxonomy: 7159)
Hierarchy Parent: CVCL_Z617 (Aag-2)
Sex of cell Sex unspecified
Age at sampling Neonate larva
Category Spontaneously immortalized cell line
Publications

PubMed=34878970; DOI=10.1099/jgv.0.001700
de Oliveira A.S., Vasconcellos A.F., Rodrigues B.M.P., da Silva L.A., Resende R.O., Ribeiro B.M.
Chikungunya virus produced by a persistently infected mosquito cell line comprises a shorter genome and is non-infectious to mammalian cells.
J. Gen. Virol. 102:001700.1-001700.11(2021)

Cross-references
Encyclopedic resources Wikidata; Q111732852
Entry history
Entry creation17-Mar-2022
Last entry update29-Jun-2023
Version number6