ID   Aag2INF
AC   CVCL_B6Y7
SY   Aag2(INF)
DR   Wikidata; Q111732852
RX   PubMed=34878970;
CC   Group: Insect cell line.
CC   Virology: Persistently infected by Chikungunya virus and Mayaro virus (PubMed=34878970).
CC   Virology: The Chikungunya virus in this cell line has accumulated non-synonymous mutations and encodes a shorter nsP3 gene and has lost the capacity to infect mammalian cells (PubMed=34878970).
CC   Anecdotal: Was accidentally created by a student that was working with Aag-2 and also manipulating samples containing arboviruses.
OX   NCBI_TaxID=7159; ! Aedes aegypti (Yellowfever mosquito)
HI   CVCL_Z617 ! Aag-2
SX   Sex unspecified
AG   Neonate larva
CA   Spontaneously immortalized cell line
DT   Created: 17-03-22; Last updated: 29-06-23; Version: 6
//
RX   PubMed=34878970; DOI=10.1099/jgv.0.001700;
RA   de Oliveira A.S., Vasconcellos A.F., Rodrigues B.M.P., da Silva L.A.,
RA   Resende R.O., Ribeiro B.M.;
RT   "Chikungunya virus produced by a persistently infected mosquito cell
RT   line comprises a shorter genome and is non-infectious to mammalian
RT   cells.";
RL   J. Gen. Virol. 102:001700.1-001700.11(2021).
//