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Cellosaurus ACRJ-PC28 (CVCL_B6XF)

[Text version]
Cell line name ACRJ-PC28
Synonyms Anti Cancer Research Jamaica-Prostate Cancer 28
Accession CVCL_B6XF
Resource Identification Initiative To cite this cell line use: ACRJ-PC28 (RRID:CVCL_B6XF)
Comments Population: Caribbean; Jamaican.
Characteristics: Lack of expression of AR (DOI=10.1158/1538-7755.DISP21-PO-138; PubMed=36643868).
Doubling time: 45 hours (DOI=10.1158/1538-7755.DISP21-PO-138; PubMed=36643868).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:1787; CDKN2A.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Web pages Info; -; -; https://www.cancer.gov/about-nci/organization/cgh/blog/2021/grantee-spotlight-badal
Publications

DOI=10.1158/1538-7755.DISP21-PO-138
Valentine H., Aiken W., Morrison B., Zhao Z.-R., Fowle H., Wasserman J.S., Thompson E., Chin W., Young M., Clarke S., Gibbs D., Harrison S., McLaughlin W., Kwok T., Jin F., Campbell K.S., Horvath A., Thompson R., Lee N.H., Zhou Y., Grana X., Ragin C.C.R., Badal-McCreath S.A.M.
The first Caribbean cell line, a prostate cancer cell line: ACRJ-PC28.
Cancer Epidemiol. Biomarkers Prev. 31 Suppl. 1:PO138-PO138(2022)

PubMed=36643868; DOI=10.1158/2767-9764.CRC-22-0245; PMCID=PMC9836004
Valentine H., Aiken W., Morrison B., Zhao Z.-R., Fowle H., Wasserman J.S., Thompson E., Chin W., Young M., Clarke S., Gibbs D., Harrison S., McLaughlin W., Kwok T., Jin F., Campbell K.S., Horvath A., Thompson R., Lee N.H., Zhou Y., Grana X., Ragin C.C.R., Badal-McCreath S.A.M.
Expanding the prostate cancer cell line repertoire with ACRJ-PC28, an AR-negative neuroendocrine cell line derived from an African-Caribbean patient.
Cancer Res. Commun. 2:1355-1371(2022)

Cross-references
Cell line collections (Providers) ABM; T0398
Encyclopedic resources Wikidata; Q111732869
Entry history
Entry creation17-Mar-2022
Last entry update10-Apr-2025
Version number8