Cellosaurus cell line TJU-UM003 (CVCL

Cross-references
Cell line name	TJU-UM003
Synonyms	UM003; Thomas Jefferson University-Uveal Melanoma 003
Accession	CVCL_B6PX
Resource Identification Initiative	To cite this cell line use: TJU-UM003 (RRID:CVCL_B6PX)
Comments	Derived from site: Metastatic; Retroperitoneal space; UBERON=UBERON_0003693.
Sequence variations	Mutation; HGNC; HGNC:4390; GNAQ; Simple; p.Gln209Leu (c.626A>T); ClinVar=VCV000375955; Zygosity=Heterozygous (PubMed=24354797; PubMed=25952648).
Disease	Uveal melanoma (NCIt: C7712) Uveal melanoma (ORDO: Orphanet_39044)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=24354797; DOI=10.1111/pcmr.12206 Yoshida M., Selvan S.R., McCue P.A., DeAngelis T., Baserga R., Fujii A., Rui H., Mastrangelo M.J., Sato T. Expression of insulin-like growth factor-1 receptor in metastatic uveal melanoma and implications for potential autocrine and paracrine tumor cell growth. Pigment Cell Melanoma Res. 27:297-308(2014) PubMed=25952648; DOI=10.1158/0008-5472.CAN-15-0370; PMCID=PMC4490069 Cheng H.-Y., Terai M., Kageyama K., Ozaki S., McCue P.A., Sato T., Aplin A.E. Paracrine effect of NRG1 and HGF drives resistance to MEK inhibitors in metastatic uveal melanoma. Cancer Res. 75:2737-2748(2015)
Cell line databases/resources	cancercelllines; CVCL_B6PX
Encyclopedic resources	Wikidata; Q112041793
Entry history
Entry creation	17-Mar-2022
Last entry update	19-Dec-2024
Version number	6