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Cellosaurus Mel Mtp (CVCL_B6KG)

[Text version]
Cell line name Mel Mtp
Synonyms mel Mtp; Mel MTP
Accession CVCL_B6KG
Resource Identification Initiative To cite this cell line use: Mel Mtp (RRID:CVCL_B6KG)
Comments Group: Patented cell line.
Registration: Non-internationally recognized Depositary Authority, Russian Cell Culture Collection (RCCC); 705D.
Derived from site: Metastatic; Right axillary lymph node; UBERON=UBERON_0001097.
Sequence variations
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (CelloPub=CLPUB00680; PubMed=30551515).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category Cancer cell line
Publications

PubMed=16107020
Mikhailova I.N., Lukashina M.I., Baryshnikov A.Y., Morozova L.F., Burova O.S., Palkina T.N., Kozlov A.M., Golubeva V.A., Cheremushkin E.A., Doroshenko M.B., Demidov L.V., Kiselev S.L., Larin S.S., Georgiev G.P.
Melanoma cell lines as the basis for antitumor vaccine preparation.
Vestn. Ross. Akad. Med. Nauk 2005:37-40(2005)

CLPUB00681
Berezhnoy A.E., Zakeyeva I.R., Kibardin A.V., Chernysheva A.D., Moiseyenko V.M., Danilov A.O., Demidov L.V., Baryshnikov A.Y., Gnuchev N.V., Georgiev G.P., Larin S.S.
Analysis of HLA-E expression in human melanoma cells.
Ross. Bioterap. Zh. 5:66-71(2006)

Patent=RU2360963
Mikhailova I.N., Baryshnikov A.Y., Demidov L.V., Kiselev S.L., Burova O.S., Morozova L.F.
Cell line of human melanoma mel Mtp used for making anticancer vaccines.
Patent number RU2360963, 10-Jul-2009

CLPUB00680
Mikhailova I.N., Baryshnikov A.Y., Morozova L.F., Burova O.S., Shubina I.Z., Kovalevsky D.A., Voronina E.S., Treshalina H.M., Lushnikova A.A., Tsyganova I.V., Mazurenko N.N.
Human skin melanoma cell lines collection.
(In) Management of malignant melanoma; None X. (eds.); pp.6.1-6.6; SM Group; Dover (2016)

PubMed=30551515; DOI=10.1016/j.biopha.2018.11.109
Ryabaya O., Prokofieva A., Akasov R., Khochenkov D., Emelyanova M., Burov S., Markvicheva E., Inshakov A., Stepanova E.V.
Metformin increases antitumor activity of MEK inhibitor binimetinib in 2D and 3D models of human metastatic melanoma cells.
Biomed. Pharmacother. 109:2548-2560(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_B6KG
Encyclopedic resources Wikidata; Q112129304
Entry history
Entry creation17-Mar-2022
Last entry update05-Oct-2023
Version number5